WebThe FGF13 gene encodes fibroblast growth factor-13, which belongs to a subclass of fibroblast growth factors expressed in the developing and adult central nervous system ( … WebSecreted FGFs have been shown to be involved in a wide range of biological processes during normal physiological development including cell differentiation in the early embryo, pattern formation, branching …

FGF13 suppresses acute myeloid leukemia by regulating bone …

WebMutation of fibroblast growth factor 13 (FGF13) has recently been implicated in genetic epilepsy with febrile seizures plus (GEFS+) in a single family segregating a balanced translocation with a breakpoint in this X chromosome gene, predicting a partial knockout … WebDec 1, 1995 · Crouzon syndrome, an autosomal dominant condition characterized by craniosynostosis, ocular proptosis and midface hypoplasia, is associated with mutations in fibroblast growth factor receptor 2 ... sanitary sewer smart covers

Fibroblast Growth Factor Homologous Factor 13 Regulates Na

WebMar 30, 2024 · Mutation of fibroblast growth factor 13 (FGF13) has recently been implicated in genetic epilepsy with febrile seizures plus (GEFS+) in … WebThis protein is part of a family of fibroblast growth factor receptors that share similar structures and functions. These receptor proteins play a role in important processes such as cell division, regulating cell growth and maturation, formation of blood vessels, wound healing, and embryo development. WebAug 2, 2013 · Moreover, analogous to loss-of-function mutations in JPH2, we hypothesize that FGF13 mutations may lead to “orphaned ryanodine receptors” that are no longer apposed to Ca V 1.2, and thus may be associated with heart failure. 20 Further studies in the appropriate model are necessary to test that hypothesis. sanitary sewer pipe size